The patient had fever, arthralgia and Raynaud's sign since July, 1999, and was diagnosed by the local hospital as Rheumatoid , and treated with tripterygium hypoglaucum hutch, no obvious effect. At December of the same year, the patient suffering from a lasting high fever (40℃), edema of face and lower limbs, came to Beijing for further treatment. The examination of local hospital: blood sedimentation was fast, Urine protein (++), antinuclear antibody (IFANA): (+), 1:180, ds-DNA<65% (+), polypeptide antibody (ENA), anti-Sm(+). And the patient diagnosed as systemic lupus erythematosus, orally took dehydrocortisone, 35mg per day, the symptom decreased，but relapse with extenuation. So the patient was admitted to our hospital on November，2003. Clinical symptoms on admission: pharyngodynia, cough, yellow sputum ease to hawk, arthralgia, chest distress and palpitation, mind lassitude and debilitation. Health examination: heart rate 100 per minute, systolic phase Ⅲ murmur can be heard on apical region. ECG: nodal tachycardia, HR: 103 per minute, T wave alteration. Echocardiogram：there were 8mm fluidity sonolucent space in posterior left ventricle, indicating：Medium dose hydropericardium mitral incompetence. X ray sternum show: left cardiac border expand slightly, cardiothoracic ratio>0.5.Laboratory examination in our hospital: there were pathological change in blood sedimentation, ANA, Liver function, anti-RNP and urine routine. urine routine: Urine protein (+),blood sedimentation 88mm/n. the lupus cell can be found in the blood sample in two time, antinuclear antibody is positive with fluorometric method; patient’s body of the tongue was red, fur of the tongue was white and slimy, the pulse was fine and rapid.
Diagnosis: systemic lupus erythematosus with carditis, hydropericardium and nephritis; heart damage syndrome caused byhaemostasis.

Treatment principle: eliminating heat by nourishing yin, induce diuresis to alleviate water retention, expelling retained fluid. Remedium cardinale is ‘zijinlangchuangjiedu pill’, 6g, three times a day, and accompanied herbs of induce diuresis and invigorating yin, such as white mulberry root bark, pericarpium arecae, tansymustard seed, fungus umbellatus, alismae rhizome, Salvia miltiorrhiza, paeoniae radix, paeoniae radix, peach seed, Curcuma aromatica, green dens draconis, one dosis per day. During our treatment period, the tripterygium hypoglaucum hutch suspended, and the hormone decrease 5mg (one pill) every week.
One month later, the patient’s condition revert to stable, even the hydropericardium disappear at one time, heart rate stable at 76 per minute, but small amounts of hydropericardium reoccur at half month’s later, so 30g Serissa serissoides (DC.)Druce was added to the former formula. After another month’s treatment, X ray sternum and ultrasound recheck indicate that the hydropericardium were absorpted complete. ECG in the next three month indicated normal electrocardiogram. The other laboratory and immunology examination result obviously improved, Urine protein (－), blood sedimentation 21mm/n，glutamic oxalacetic transaminase and glutamate-pyruvate transaminase all below 30, no lupus cell found in blood sample, antinuclear antibody (+), 1:60. The patient had been in our hospital for 139 days. During the whole process of treatment, the hormone was suspended in 40 days. and after the hydropericardium disappear, the patient took ‘zijinlangchuangjiedu pill’ only, and never took the other immunodepressant and emictory, follow-up by out-patient clinic indicating that the patient had return to a normal life and work.